Article
The GPIIIA PlA2 polymorphism is associated with an increased risk of cardiovascular adverse events.
BMC cardiovascular disorders - 16 Sept 2010
Galasso Gennaro, Santulli Gaetano, Piscione Federico, De Rosa Roberta, Trimarco Valentina, Piccolo Raffaele, Cassese Salvatore, Iaccarino Guido, Trimarco Bruno, Chiariello Massimo
Abstract excerpt
BACKGROUND: The clinical impact of PlA2 polymorphism has been investigated in several diseases, but the definition of its specific role on thrombotic cardiovascular complications has been challenging. We aimed to explore the effect of PlA2 polymorphism on outcome in patients with atherosclerosis. METHODS: We studied 400 consecutive patients with coronary artery disease (CAD) undergoing percutaneous coronary...
Topics
- Aged
- Alleles
- Atherosclerosis
- Coronary Artery Disease
- Coronary Thrombosis
- Female
- Follow-Up Studies
- Humans
- Integrin alphaVbeta3
- Integrin beta3
- Male
- Middle Aged
- Polymorphism, Genetic