PIA1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis.

doi:10.1016/S0140-6736(97)80010-4

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Article

PIA1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis.

Lancet (London, England) - 8 Feb 1997

Ridker P M, Hennekens C H, Schmitz C, Stampfer M J, Lindpaintner K

Abstract excerpt

BACKGROUND: The gene encoding the platelet glycoprotein IIIa receptor (GPIIIa), shows polymorphism (PIA1/A2). In a previous study, men with acute coronary ischaemia were more likely than controls to carry the PIA2 allele. This receptor has an important role in acute thrombus formation; these find...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Aspirin
Body Mass Index
Cerebrovascular Disorders
Cohort Studies
DNA
Humans
Male
Middle Aged
Myocardial Infarction
Platelet Glycoprotein GPIIb-IIIa Complex
Point Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 9033464
DOI: 10.1016/S0140-6736(97)80010-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9033464-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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