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Article

Fibrinogen Polymorphisms and Atherothrombotic Disease

1 Jun 2001

Abstract excerpt

Common polymorphisms of the fibrinogen gene cluster are associated with circulating fibrinogen level and with susceptibility to and/or severity of atherothrombotic disease. The frequencies of the polymorphisms vary among different ethnic groups but there is strong linkage disequilibrium at the beta-fibrinogen gene locus so that, in caucasian populations, there are only four common beta-fibrinogen haplotypes. One...

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PMID: 11460514
DOI: 10.1111/j.1749-6632.2001.tb03543.x

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