Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between the TPH gene A218C polymorphism and suicidal behavior: a meta-analysis.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2004

Bellivier Frank, Chaste Pauline, Malafosse Alain

Abstract excerpt

Genes encoding proteins involved in serotonergic metabolism are major candidates in association studies of suicidal behavior. The tryptophan hydroxylase (TPH) gene, which codes for the rate-limiting enzyme of serotonin biosynthesis, is a major candidate gene and has been extensively studied in association studies of suicidal behavior, providing conflicting results. It is difficult to interpret these conflicting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Odds Ratio

Share to Polymorphism, Genetic

Share to Suicide

Share to Suicide, Attempted

Share to Tryptophan Hydroxylase

Source

Identifiers

PMID: 14681922
DOI: 10.1002/ajmg.b.20015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between the TPH gene A218C polymorphism and suicidal behavior: a meta-analysis.PMID 14681922Read ↗

Genetic variations in tryptophan hydroxylase in suicidal behavior: analysis and meta-analysis.Semantic proximity Read ↗

Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.Semantic proximity Read ↗

TPH1 A218 allele is associated with suicidal behavior in Turkish population.Semantic proximity Read ↗

Further clarification of the contribution of the tryptophan hydroxylase (TPH) gene to suicidal behavior using systematic allelic and genotypic meta-analyses.Semantic proximity Read ↗

Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors.Semantic proximity Read ↗

Investigation of A218C tryptophan hydroxylase polymorphism: association with familial suicide behavior and proband's suicide attempt characteristics.Semantic proximity Read ↗

The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis.Semantic proximity Read ↗

Serotonergic genes and suicide: a systematic review.Semantic proximity Read ↗

An association study of suicide and candidate genes in the serotonergic system.Semantic proximity Read ↗

TPH gene may be associated with suicidal behavior, but not with schizophrenia in the Korean population.Semantic proximity Read ↗

Effect of SNP at position 40237 in exon 7 of the TPH2 gene on susceptibility to suicide.Semantic proximity Read ↗

Association analysis of TPH-1 and TPH-2 genes with suicidal behavior in patients with attempted suicide in Mexican population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.