TPH1 A218 allele is associated with suicidal behavior in Turkish population.

doi:10.1016/j.legalmed.2016.05.005

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Article

TPH1 A218 allele is associated with suicidal behavior in Turkish population.

Legal medicine (Tokyo, Japan) - 1 Jul 2016

Beden Onur, Senol Ender, Atay Sevcan, Ak Handan, Altintoprak Ayse Ender, Kiyan Guclu Selahattin, Petin Buket, Yaman Utku, Aydin Hikmet Hakan

Abstract excerpt

BACKGROUND: Serotonergic dysfunction is implicated in depression, psychiatric disorders and suicidal behaviors. The first and rate-limiting step in the synthesis of serotonin is catalyzed by tryptophan hydroxylase (TPH) which is encoded by TPH1 and THP2 genes. Genetic association studies have revealed contradictory results about the effect of the TPH1 A218C (rs1800532) polymorphism on suicidal behavior in...

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Identifiers

PMID: 27497328
DOI: 10.1016/j.legalmed.2016.05.005

Genes

TPH1

Variants

rs1800532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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TPH1 A218 allele is associated with suicidal behavior in Turkish population.PMID 27497328Read ↗

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