Serotonergic genes and suicide: a systematic review.

doi:10.1016/j.euroneuro.2013.03.013

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Article

Serotonergic genes and suicide: a systematic review.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Oct 2013

Antypa Niki, Serretti Alessandro, Rujescu Dan

Abstract excerpt

Suicide is one of the leading causes of death in the world. Its aetiology is complex and diverse, however, epidemiological studies show that suicidal behavior is partly heritable. Neurobiological evidence implicates serotonergic dysfunction in suicidality, stimulating genetic research to focus on genes related to the serotonergic system. In this paper, we review evidence from studies examining the association...

Topics

Alleles
Animals
Brain
Case-Control Studies
Endophenotypes
Evidence-Based Medicine
Gene-Environment Interaction
Genetic Association Studies
Genetic Predisposition to Disease
Genetic Variation
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Monoamine Oxidase

Nerve Tissue Proteins

Neurons

Protein Isoforms

Receptors, Serotonin

Self-Injurious Behavior

Serotonin Plasma Membrane Transport Proteins

Source

Open in PubMed

Identifiers

PMID: 23742855
DOI: 10.1016/j.euroneuro.2013.03.013

Genes

MAOA
TPH1
TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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