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Article

Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.

BMC psychiatry - 8 Jul 2014

González-Castro Thelma Beatriz, Juárez-Rojop Isela, López-Narváez María Lilia, Tovilla-Zárate Carlos Alfonso

Abstract excerpt

BACKGROUND: It is widely acknowledged that suicidal behavior (SB) has a genetic influence. As a consequence, molecular genetic studies have been mostly conducted on serotonergic genes. One of the most promising candidate genes of this system is tryptophan hydroxylase (TPH). Although there have been several positive studies associating TPH genes and SB, the evidence is not entirely consistent. Therefore, we...

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Source

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Identifiers

PMID: 25005534
DOI: 10.1186/1471-244X-14-196
PMCID: PMC4099217

Genes

TPH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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