Article
Tag SNP selection for candidate gene association studies using HapMap and gene resequencing data.
European journal of human genetics : EJHG - 1 Oct 2007
Xu Zongli, Kaplan Norman L, Taylor Jack A
Abstract excerpt
HapMap provides linkage disequilibrium (LD) information on a sample of 3.7 million SNPs that can be used for tag SNP selection in whole-genome association studies. HapMap can also be used for tag SNP selection in candidate genes, although its performance has yet to be evaluated against gene resequencing data, where there is near-complete SNP ascertainment. The Environmental Genome Project (EGP) is the largest...
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