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Article

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.

Proceedings of the National Academy of Sciences of the United States of America - 9 Jun 2009

Hindorff Lucia A, Sethupathy Praveen, Junkins Heather A, Ramos Erin M, Mehta Jayashri P, Collins Francis S, Manolio Teri A

Abstract excerpt

We have developed an online catalog of SNP-trait associations from published genome-wide association studies for use in investigating genomic characteristics of trait/disease-associated SNPs (TASs). Reported TASs were common [median risk allele frequency 36%, interquartile range (IQR) 21%-53%] and were associated with modest effect sizes [median odds ratio (OR) 1.33, IQR 1.20-1.61]. Among 20 genomic annotation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19474294
DOI: 10.1073/pnas.0903103106
PMCID: PMC2687147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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