Article
Efficient selection of tagging single-nucleotide polymorphisms in multiple populations.
Human genetics - 1 Aug 2006
Howie Bryan N, Carlson Christopher S, Rieder Mark J, Nickerson Deborah A
Abstract excerpt
Common genetic polymorphism may explain a portion of the heritable risk for common diseases, so considerable effort has been devoted to finding and typing common single-nucleotide polymorphisms (SNPs) in the human genome. Many SNPs show correlated genotypes, or linkage disequilibrium (LD), suggesting that only a subset of all SNPs (known as tagging SNPs, or tagSNPs) need to be genotyped for disease association...
Topics
- Algorithms
- Asian People
- Black People
- Genetics, Population
- Genotype
- Humans
- Linkage Disequilibrium
- Polymorphism, Single Nucleotide
- White People