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Genetic control of meiosis surveillance mechanisms in mammals

23 Feb 2023

Abstract excerpt

Meiosis is a specialized cell division that generates haploid gametes and is critical for successful sexual reproduction. During the extended meiotic prophase I, homologous chromosomes progressively pair, synapse and desynapse. These chromosomal dynamics are tightly integrated with meiotic recombination (MR), during which programmed DNA double-strand breaks (DSBs) are formed and subsequently repaired....

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PMID: 36910159
DOI: 10.3389/fcell.2023.1127440

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