Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination

18 Jul 2025

Abstract excerpt

Three critical and interdependent processes define meiotic prophase I: homologous chromosomes must pair together, a proteinaceous structure called the synaptonemal complex forms to tether homologs together (synapsis), and homologs undergo recombination, reciprocally exchanging genetic material to form crossovers (COs). Errors in these processes can result in premature ovarian insufficiency, aneuploidy, and...

Topics

Join the communities discussing this publication.

Pluripotent Stem Cells Research
Reproductive Biology and Fertility

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40758596
DOI: 10.3791/68749

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and RecombinationPMID 40758596Read ↗

Chromosome length is not the sole determinant of sexually dimorphic crossover rates during mammalian meiosis: Insights from genetically diverse mouse strainsSemantic proximity Read ↗

Distinct cellular and reproductive consequences of meiotic chromosome synapsis defects in syce2 and sycp1 mutant zebrafish.Semantic proximity Read ↗

Chromatin Spread Preparations for the Analysis of Mouse Oocyte Progression from Prophase to Metaphase IISemantic proximity Read ↗

Genetic control of meiosis surveillance mechanisms in mammalsSemantic proximity Read ↗

The DNA Damage Checkpoint Eliminates Mouse Oocytes with Chromosome Synapsis Failure.Semantic proximity Read ↗

Structural damage to meiotic chromosomes impairs DNA recombination and checkpoint control in mammalian oocytes.Semantic proximity Read ↗

Genetic analysis of chromosome pairing, recombination, and cell cycle control during first meiotic prophase in mammals.Semantic proximity Read ↗

Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes.Semantic proximity Read ↗

The telomere bouquet is a hub where meiotic double-strand breaks, synapsis, and stable homolog juxtaposition are coordinated in the zebrafish, Danio rerioSemantic proximity Read ↗

Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3.Semantic proximity Read ↗

Chiasmata, crossovers, and meiotic chromosome segregation.Semantic proximity Read ↗

Zebrafish lack a strong meiotic checkpoint response to defects in chromosome synapsisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.