Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zic2 is required for neural crest formation and hindbrain patterning during mouse development.

Developmental biology - 15 Dec 2003

Elms Paul, Siggers Pam, Napper Diane, Greenfield Andy, Arkell Ruth

Abstract excerpt

The Zic genes are the vertebrate homologues of the Drosophila pair rule gene odd-paired. It has been proposed that Zic genes play several roles during neural development including mediolateral segmentation of the neural plate, neural crest induction, and inhibition of neurogenesis. Initially during mouse neural development Zic2 is expressed throughout the neural plate while later on expression in the neurectoderm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Cell Count
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Movement

Share to Mice, Inbred C3H

Share to Neural Crest

Share to Rhombencephalon

Share to Transcription Factors

Source

Identifiers

PMID: 14651926
DOI: 10.1016/j.ydbio.2003.09.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zic2 is required for neural crest formation and hindbrain patterning during mouse development.PMID 14651926Read ↗

Zic2 regulates the kinetics of neurulation.Semantic proximity Read ↗

The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes.Semantic proximity Read ↗

Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis.Semantic proximity Read ↗

Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo.Semantic proximity Read ↗

Zebrafish Zic2a and Zic2b regulate neural crest and craniofacial development.Semantic proximity Read ↗

Zic2 controls cerebellar development in cooperation with Zic1.Semantic proximity Read ↗

The ZIC gene family encodes multi-functional proteins essential for patterning and morphogenesis.Semantic proximity Read ↗

Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation.Semantic proximity Read ↗

Dual role of ZIC2 during neural induction: from pioneer transcription factor to enhancer activatorSemantic proximity Read ↗

The ZIC gene family in development and disease.Semantic proximity Read ↗

Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve gangliaSemantic proximity Read ↗

Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.