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Article

Zic2 controls cerebellar development in cooperation with Zic1.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jan 2002

Aruga Jun, Inoue Takashi, Hoshino Jun, Mikoshiba Katsuhiko

Abstract excerpt

Mouse Zic genes encode zinc finger proteins and are expressed in the developing and mature CNS. Reduced expression of Zic2 in mice results in spina bifida and holoprosencephaly. However, the disruption of Zic1, a strong homolog of Zic2 that has an overlapping expression pattern, results in cerebellar malformation with no apparent abnormalities in the forebrain or in posterior neuropore closure. Here we revealed...

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Identifiers

PMID: 11756505
PMCID: PMC6757594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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