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Article

Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis.

Developmental biology - 15 Feb 2008

Elsen Gina E, Choi Louis Y, Millen Kathleen J, Grinblat Yevgenya, Prince Victoria E

Abstract excerpt

During development, the lumen of the neural tube develops into a system of brain cavities or ventricles, which play important roles in normal CNS function. We have established that the formation of the hindbrain (4th) ventricle in zebrafish is dependent upon the pleiotropic functions of the genes implicated in human Dandy Walker Malformation, Zic1 and Zic4. Using morpholino knockdown we show that zebrafish Zic1...

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Identifiers

PMID: 18191121
DOI: 10.1016/j.ydbio.2007.12.006
PMCID: PMC2268115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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