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Article

Zebrafish Zic2a and Zic2b regulate neural crest and craniofacial development.

Developmental biology - 1 Aug 2013

Teslaa Jessica J, Keller Abigail N, Nyholm Molly K, Grinblat Yevgenya

Abstract excerpt

Holoprosencephaly (HPE), the most common malformation of the human forebrain, is associated with defects of the craniofacial skeleton. ZIC2, a zinc-finger transcription factor, is strongly linked to HPE and to a characteristic set of dysmorphic facial features in humans. We have previously identified important functions for zebrafish Zic2 in the developing forebrain. Here, we demonstrate that ZIC2 orthologs zic2a...

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Source

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Identifiers

PMID: 23665173
DOI: 10.1016/j.ydbio.2013.04.033
PMCID: PMC3886643

Genes

ZIC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Zebrafish Zic2a and Zic2b regulate neural crest and craniofacial development.PMID 23665173Read ↗

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