Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis.

Developmental biology - 1 Sept 2017

Sedykh Irina, Yoon Baul, Roberson Laura, Moskvin Oleg, Dewey Colin N, Grinblat Yevgenya

Abstract excerpt

The vertebrate retina develops in close proximity to the forebrain and neural crest-derived cartilages of the face and jaw. Coloboma, a congenital eye malformation, is associated with aberrant forebrain development (holoprosencephaly) and with craniofacial defects (frontonasal dysplasia) in humans, suggesting a critical role for cross-lineage interactions during retinal morphogenesis. ZIC2, a zinc-finger...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cartilage
Share to Choroid
Share to Coloboma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neural Crest

Share to PAX2 Transcription Factor

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28689736
DOI: 10.1016/j.ydbio.2017.07.003
PMCID: PMC5603172

Genes

ZIC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis.PMID 28689736Read ↗

Zebrafish Zic2a and Zic2b regulate neural crest and craniofacial development.Semantic proximity Read ↗

The ZIC gene family encodes multi-functional proteins essential for patterning and morphogenesis.Semantic proximity Read ↗

The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes.Semantic proximity Read ↗

The ZIC gene family in development and disease.Semantic proximity Read ↗

Zfp503/Nlz2 is Required for RPE Differentiation and Optic Fissure ClosureSemantic proximity Read ↗

Dual role of ZIC2 during neural induction: from pioneer transcription factor to enhancer activatorSemantic proximity Read ↗

Zic2 is required for neural crest formation and hindbrain patterning during mouse development.Semantic proximity Read ↗

Zic2 regulates the kinetics of neurulation.Semantic proximity Read ↗

Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closureSemantic proximity Read ↗

Identification of novel coloboma candidate genes through conserved gene expression analyses across four vertebrate speciesSemantic proximity Read ↗

Zic2 mutation causes holoprosencephaly via disruption of NODAL signalling.Semantic proximity Read ↗

Expression of a novel zebrafish zinc finger gene, gli2b, is affected in Hedgehog and Notch signaling related mutants during embryonic development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.