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Article

The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2014

Chervenak Andrew P, Bank Lisa M, Thomsen Nicole, Glanville-Jones Hannah C, Jonathan Skibo, Millen Kathleen J, Arkell Ruth M, Barald Kate F

Abstract excerpt

BACKGROUND: Murine Zic genes (Zic1-5) are expressed in the dorsal hindbrain and in periotic mesenchyme (POM) adjacent to the developing inner ear. Zic genes are involved in developmental signaling pathways in many organ systems, including the ear, although their exact roles haven't been fully elucidated. This report examines the role of Zic1, Zic2, and Zic4 during inner ear development in mouse mutants in which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25178196
DOI: 10.1002/dvdy.24186
PMCID: PMC4206579

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