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Article

Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating.

Neuron - 13 Nov 2003

Verstreken Patrik, Koh Tong-Wey, Schulze Karen L, Zhai R Grace, Hiesinger P Robin, Zhou Yi, Mehta Sunil Q, Cao Yu, Roos Jack, Bellen Hugo J

Abstract excerpt

We describe the isolation and characterization of Drosophila synaptojanin (synj) mutants. synj encodes a phosphatidylinositol phosphatase involved in clathrin-mediated endocytosis. We show that Synj is specifically localized to presynaptic terminals and is associated with synaptic vesicles. The electrophysiological and ultrastructural defects observed in synj mutants are strikingly similar to those found in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 14622578
DOI: 10.1016/s0896-6273(03)00644-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating.PMID 14622578Read ↗

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