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Article

Synaptophysin: leading actor or walk-on role in synaptic vesicle exocytosis?

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Apr 2004

Valtorta Flavia, Pennuto Maria, Bonanomi Dario, Benfenati Fabio

Abstract excerpt

Synaptophysin (Syp) was the first synaptic vesicle (SV) protein to be cloned. Since its discovery in 1985, it has been used by us and by many laboratories around the world as an invaluable marker to study the distribution of synapses in the brain and to uncover the basic features of the life cycle of SVs. Although single gene ablation of Syp does not lead to an overt phenotype, a large body of experimental data...

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PMID: 15057942
DOI: 10.1002/bies.20012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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