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Article

Essential functions of synapsins I and II in synaptic vesicle regulation.

Nature - 8 Jun 1995

Rosahl T W, Spillane D, Missler M, Herz J, Selig D K, Wolff J R, Hammer R E, Malenka R C, Südhof T C

Abstract excerpt

Synaptic vesicles are coated by synapsins, phosphoproteins that account for 9% of the vesicle protein. To analyse the functions of these proteins, we have studied knockout mice lacking either synapsin I, synapsin II, or both. Mice lacking synapsins are viable and fertile with no gross anatomical abnormalities, but experience seizures with a frequency proportional to the number of mutant alleles. Synapsin-II and...

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PMID: 7777057
DOI: 10.1038/375488a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Essential functions of synapsins I and II in synaptic vesicle regulation.PMID 7777057Read ↗

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