Article
Essential role of endophilin A in synaptic vesicle budding at the Drosophila neuromuscular junction.
The EMBO journal - 2 Apr 2002
Guichet Antoine, Wucherpfennig Tanja, Dudu Veronica, Etter Sylvain, Wilsch-Bräuniger Michaela, Hellwig Andrea, González-Gaitán Marcos, Huttner Wieland B, Schmidt Anne A
Abstract excerpt
We characterized Drosophila endophilin A (D-endoA), and generated and analysed D-endoA mutants. Like its mammalian homologue, D-endoA exhibits lysophosphatidic acid acyl transferase activity and contains a functional SH3 domain. D-endoA is recruited to the sites of endocytosis, as revealed by immunocytochemistry of the neuromuscular junction (NMJ) of mutant L3 larvae carrying the temperature-sensitive allele of...
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