Article
Endophilin promotes a late step in endocytosis at glial invaginations in Drosophila photoreceptor terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 19 Nov 2003
Fabian-Fine Ruth, Verstreken Patrik, Hiesinger P Robin, Horne Jane Anne, Kostyleva Rita, Zhou Yi, Bellen Hugo J, Meinertzhagen Ian A
Abstract excerpt
Retrieval of synaptic vesicles from the membrane of neurons is crucial to maintain normal rates of neurotransmitter release. Photoreceptor terminals of the fly's eye release neurotransmitter in a tonic manner. They therefore rely heavily on vesicle regeneration. Null mutations in endophilin (endo) block clathrin-mediated endocytosis at the Drosophila neuromuscular junction, where previous analysis of hypomorphic...
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