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Article

Polymorphonuclear granulocytes induce antibody-dependent apoptosis in human breast cancer cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2003

Stockmeyer Bernhard, Beyer Thomas, Neuhuber Winfried, Repp Roland, Kalden Joachim R, Valerius Thomas, Herrmann Martin

Abstract excerpt

Recent studies in HER-2/neu-targeted immunotherapy demonstrated that polymorphonuclear neutrophils (PMN) mediated Ab-dependent cellular cytotoxicity against HER-2/neu-positive breast cancer cell lines. However, the mechanism of cell death remained unclear. We used several assays to analyze the induction of apoptosis in the breast cancer cell line SK-BR-3 via PMN-dependent Ab-dependent cellular cytotoxicity. In...

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Identifiers

PMID: 14607911
DOI: 10.4049/jimmunol.171.10.5124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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