Article
Spontaneous apoptosis of blood dendritic cells in patients with breast cancer.
Breast cancer research : BCR - 1 Jan 2006
Pinzon-Charry Alberto, Maxwell Tammy, McGuckin Michael A, Schmidt Chris, Furnival Colin, López J Alejandro
Abstract excerpt
INTRODUCTION: Dendritic cells (DCs) are key antigen-presenting cells that play an essential role in initiating and directing cellular and humoral immunity, including anti-tumor responses. Due to their critical role in cancer, induction of DC apoptosis may be one of the central mechanisms used by tumors to evade immune recognition. METHODS: Spontaneous apoptosis of blood DCs (lineage negative HLA-DR positive...
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