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Article

Mechanistic analysis of the antitumor efficacy of human natural killer cells against breast cancer cells.

Breast cancer research and treatment - 1 Jul 2012

Kajitani Keiko, Tanaka Yuka, Arihiro Koji, Kataoka Tsuyoshi, Ohdan Hideki

Abstract excerpt

We investigated the role of human natural killer (NK) cells in the peripheral blood (PB) and liver in controlling breast cancer. The proportion of NK cells among liver mononuclear cells was significantly higher than among PB mononuclear cells. Liver NK cells inductively expressed higher levels of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) than PB NK cells in response to interleukin-2 (IL-2)....

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Share to Antibodies, Monoclonal, Humanized
Share to Antibody-Dependent Cell Cytotoxicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22261932
DOI: 10.1007/s10549-011-1944-x

Genes

CXCL10
CXCR3
CXCL11
CXCL9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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