Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation.

Mutagenesis - 1 May 2005

Decordier Ilse, Cundari Enrico, Kirsch-Volders Micheline

Abstract excerpt

Aneugenic and clastogenic agents are good inducers of both micronuclei and apoptosis. In its turn, apoptosis may modify the threshold values for the induction of micronuclei. This is of major concern for accurate assessment of hazard related to exposure to mutagens. In the present work we studied the influence of caspases, the key regulators of the apoptotic process, on the induction of micronuclei in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caspase 7
Share to Caspase 8
Share to Caspase Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cysteine Proteinase Inhibitors

Share to Micronuclei, Chromosome-Defective

Share to Micronucleus Tests

Share to Nocodazole

Share to Staurosporine

Source

Identifiers

PMID: 15817572
DOI: 10.1093/mutage/gei025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation.PMID 15817572Read ↗

Micronuclei assay by laser scanning cytometrySemantic proximity Read ↗

Clinical application of micronucleus test: a case-control study on the prediction of breast cancer risk/susceptibility.Semantic proximity Read ↗

Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubulesSemantic proximity Read ↗

Role of micronucleus test in predicting breast cancer susceptibility: a systematic review and meta-analysis.Semantic proximity Read ↗

Mechanism of Acetaminophen-Induced Apoptosis in Cultured Cells: Roles of Caspase-3, DNA Fragmentation Factor, and the Ca2+ and Mg2+ Endonuclease DNAS1L3Semantic proximity Read ↗

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis.Semantic proximity Read ↗

Induction of micronuclei by four cytostatic compounds in human hematopoietic stem cells and human lymphoblastoid TK6 cells.Semantic proximity Read ↗

Evaluation of the genotoxic and antigenotoxic effects of Chios mastic water by the in vitro micronucleus test on human lymphocytes and the in vivo wing somatic test on Drosophila.Semantic proximity Read ↗

Assessment of complex genomic alterations induced by AZT, 3TC, and the combination AZT +3TC.Semantic proximity Read ↗

Assessment of in vivo chemotherapy-induced DNA damage in a p53-mutated rat tumor by micronuclei assay.Semantic proximity Read ↗

Micronuclei and mitotic index in B-, T4- and T8-cells treated with mitomycin C and gamma-irradiation.Semantic proximity Read ↗

Polymorphonuclear granulocytes induce antibody-dependent apoptosis in human breast cancer cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.