Article
Molecular characterization of the surface of apoptotic neutrophils: implications for functional downregulation and recognition by phagocytes.
Cell death and differentiation - 1 May 2000
Hart S P, Ross J A, Ross K, Haslett C, Dransfield I
Abstract excerpt
We have used a panel of monoclonal antibodies and lectins to examine the profile of surface molecule expression on human neutrophils that have undergone spontaneous apoptosis during in vitro culture. Neutrophil apoptosis was found to be accompanied by down-regulation of the immunoglobulin superfamily members PECAM-1 (CD31), ICAM-3 (CD50), CD66acde, and CD66b and the integrin-associated proteins CD63 and urokinase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
