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Article

Gene expression of NS5a strong antigenic regions of hepatitis C virus in E.coli and detection of their antigenicity.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Aug 2002

Dou Xiao-Guang, Feng Guo-He, Shi Li-Lan, Fields Howard

Abstract excerpt

OBJECTIVE: To study the effect of sequence variability between different genotypes of HCV on the antigenic properties of the NS5a protein of strong antigenic region at position 2212-2313 by using recombinant proteins. METHODS: Thirteen representative sequences from HCV genotypes 1 to 6 were selected to design synthetic genes encoding for this antigenic region. These genes were assembled by PCR from synthetic...

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PMID: 14607711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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