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Article

Immunogenicity of variable regions of hepatitis C virus proteins: selection and modification of peptide epitopes to assess hepatitis C virus genotypes by ELISA.

The Journal of general virology - 1 Mar 1999

Rodr Guez-L Pez M, Riezu-Boj J I, Ruiz M, Berasain C, Civeira M P, Prieto J, Borr S-Cuesta F

Abstract excerpt

The immunogenicity of variable regions of hepatitis C virus (HCV) proteins was studied by ELISA by using 543 synthetic peptides from 120 variable regions and 90 sera from HCV-infected patients. Some regions from certain genotypes were less immunogenic, or even non-immunogenic, compared with their equivalents in other genotypes. However, the mean recognition of all peptides from genotypes 1a, 1b and 3 by sera...

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Source

Identifiers

PMID: 10092013
DOI: 10.1099/0022-1317-80-3-727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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