Article
[Immunoreactivity studies on synthetic peptides deriving from immunodominant region of hepatitis C virus NS5a gene].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Dec 2004
Shi Li-lan, Dou Xiao-guang, Feng Guo-he, Fields Howard, Khudyakov Yuri
Abstract excerpt
OBJECTIVE: To identify the location of major immunodominant antigenic region and study the relationship between the gene heterogeneity and immunoreactivity via detecting antigenic reactivity of synthetic peptides deriving from immunodominant region in different genotypes of hepatitis C virus (HCV) NS5a gene. METHODS: In total, 305 non-identical 30-mer long and overlapping by 15 aa peptides derived from HCV NS5a...
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