Article
Expression of hepatitis C virus hypervariable region 1 and its clinical significance.
World journal of gastroenterology - 1 May 2003
Zhang Xin-Xin, Zhang Shen-Ying, Liu Jing, Lu Zhi-Meng, Wang Yuan
Abstract excerpt
AIM: To explore the properties of hypervariable region 1 (HVR1) in the envelope 2 gene of hepatitis C virus by analyzing the reactivity of HVR1 fusion proteins from different Chinese HCV strains with sera of patients with chronic hepatitis C and by comparing their reactivity between interferon therapy responders and non-responders. METHODS: Gene fragments of HVR1 of four HCV strains (three genotype 1b and one...
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