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Article

Sequence variation upstream of precore translation initiation codon reduces hepatitis B virus e antigen production.

Gastroenterology - 1 Nov 2003

Ahn Sang Hoon, Kramvis Anna, Kawai Shigenobu, Spangenberg Hans Christian, Li Jisu, Kimbi Gerald, Kew Michael, Wands Jack, Tong Shuping

Abstract excerpt

BACKGROUND & AIMS: Most South African hepatitis B virus strains harbor point mutations immediately upstream of the precore AUG codon. The aim of this study was to determine their effect on hepatitis B e antigen expression. METHODS: The hepatitis B virus DNA sequence around the precore region was determined from sera of 45 black South Africans. The South African mutations were introduced into hepatitis B virus...

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Identifiers

PMID: 14598253
DOI: 10.1016/j.gastro.2003.07.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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