Replication capacities of natural and artificial precore stop codon mutants of hepatitis B virus: relevance of pregenome encapsidation signal.

doi:10.1016/0042-6822(92)90185-r

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Article

Replication capacities of natural and artificial precore stop codon mutants of hepatitis B virus: relevance of pregenome encapsidation signal.

Virology - 1 Nov 1992

Tong S P, Li J S, Vitvitski L, Trépo C

Abstract excerpt

The emergence of hepatitis B virus variants unable to express HBe protein during late stage of viral infection may represent an important mechanism of viral persistence. The molecular mechanisms responsible for the elimination of HBe expression are nonsense or frameshift mutations or initiation c...

Topics

Base Sequence
Capsid
Codon
DNA Replication
DNA, Viral
Genetic Complementation Test
Genome, Viral
Hepatitis B e Antigens
Hepatitis B virus
Humans
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA, Viral
Transfection
Tumor Cells, Cultured
Virus Replication

Source

Open in PubMed

Identifiers

PMID: 1413504
DOI: 10.1016/0042-6822(92)90185-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1413504-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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