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Article

Hepatitis B virus precore mutants in serum and liver of Southern African Blacks with hepatocellular carcinoma.

Journal of hepatology - 1 Jan 1998

Kramvis A, Kew M C, Bukofzer S

Abstract excerpt

BACKGROUND/AIM: The aim of this study was to sequence the precore region of HBV isolated from serum and tumorous and non-tumorous liver tissue from patients with hepatocellular carcinoma to identify mutations that might play a role in malignant transformation. METHODS: HBV DNA was extracted from 62 sera, 14 tumorous and 12 non-tumorous liver tissue samples of patients with hepatocellular carcinoma, amplified by...

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PMID: 9537850
DOI: 10.1016/s0168-8278(98)80212-2

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Hepatitis B virus precore mutants in serum and liver of Southern African Blacks with hepatocellular carcinoma.PMID 9537850Read ↗

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