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Article

Hepatitis B virus precore mutants in serum and liver of Southern African Blacks with hepatocellular carcinoma.

Journal of hepatology - 1 Jan 1998

Kramvis A, Kew M C, Bukofzer S

Abstract excerpt

BACKGROUND/AIM: The aim of this study was to sequence the precore region of HBV isolated from serum and tumorous and non-tumorous liver tissue from patients with hepatocellular carcinoma to identify mutations that might play a role in malignant transformation. METHODS: HBV DNA was extracted from...

Topics

Adult
Amino Acid Sequence
Base Sequence
Black People
Carcinoma, Hepatocellular
Codon, Terminator
DNA, Viral
Guanine
Hepatitis B e Antigens
Hepatitis B virus
Humans
Liver
Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Point Mutation

Polymerase Chain Reaction

Sequence Alignment

Source

Identifiers

PMID: 9537850
DOI: 10.1016/s0168-8278(98)80212-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9537850-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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