Article
Hepatitis B virus precore mutants are identical in carriers from various ethnic origins and are associated with a range of liver disease severity.
Hepatology (Baltimore, Md.) - 1 Dec 1992
Tur-Kaspa R, Klein A, Aharonson S
Abstract excerpt
Hepatitis B virus carriers in Israel are mostly HBeAg negative, of whom 5% to 10% have circulating hepatitis B virus. Recently, a hepatitis B virus variant with a stop codon in the precore region was identified, and it was suggested that specific mutations are associated with fulminant or severe chronic active hepatitis. We have analyzed serum samples from HBeAg-positive and HBeAg-negative patients by polymerase...
Topics
- Adult
- Aged
- Base Sequence
- Carrier State
- DNA, Viral
- Ethnicity
- Female
- Hepatitis B
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Liver Diseases