Article
Nucleic acid sequence analysis of the precore region of hepatitis B virus from sera of southern African black adult carriers of the virus.
Hepatology (Baltimore, Md.) - 1 Jan 1997
Kramvis A, Bukofzer S, Kew M C, Song E
Abstract excerpt
Our purpose was to ascertain if mutations of the precore region of the hepatitis B virus genome, in particular the 1896 stop codon mutation, are responsible for the 95% hepatitis B e antigen (HBeAg)-negativity rate in southern African black adult carriers. Hepatitis B virus (HBV) DNA was extracted from the serum of 57 asymptomatic carriers (42 HBeAg-negative; 15 HBeAg-positive), the precore region was amplified...
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