Nucleic acid sequence analysis of the precore region of hepatitis B virus from sera of southern African black adult carriers of the virus.

doi:10.1002/hep.510250143

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Article

Nucleic acid sequence analysis of the precore region of hepatitis B virus from sera of southern African black adult carriers of the virus.

Hepatology (Baltimore, Md.) - 1 Jan 1997

Kramvis A, Bukofzer S, Kew M C, Song E

Abstract excerpt

Our purpose was to ascertain if mutations of the precore region of the hepatitis B virus genome, in particular the 1896 stop codon mutation, are responsible for the 95% hepatitis B e antigen (HBeAg)-negativity rate in southern African black adult carriers. Hepatitis B virus (HBV) DNA was extracte...

Topics

Adult
Amino Acid Sequence
Base Sequence
Carrier State
DNA, Viral
Hepatitis B
Hepatitis B e Antigens
Hepatitis B virus
Humans
Molecular Sequence Data
Mutation
Viremia

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