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Article

High-resolution genotyping of chromosome 8 in colon adenocarcinomas reveals recurrent break point but no gene mutation in the 8p21 region.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Jun 2008

Mourra Najat, Zeitoun Guy, Portier Guillaume, Blanche Hélène, Tubacher Emmanuel, Gressin Laetitia, Flejou Jean-François, Tiret Emmanuel, Thomas Gilles, Olschwang Sylviane

Abstract excerpt

The prognosis of patients with colorectal cancer is largely determined by the tumor stage. In this respect, colorectal cancer with lymph node metastases has the worst prognosis. Accordingly, there is considerable clinical interest in understanding the genetic mechanisms underlying metastasis formation. The short arm of chromosome 8 is often lost in colorectal cancer and has been associated with the advanced...

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PMID: 18382363
DOI: 10.1097/PDM.0b013e31815bb5eb

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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