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Article

High frequency of chromosome 14 deletion in early-onset colon cancer.

Diseases of the colon and rectum - 1 Nov 2007

Mourra Najat, Zeitoun Guy, Buecher Bruno, Finetti Pascal, Lagarde Arnaud, Adelaide José, Birnbaum Daniel, Thomas Gilles, Olschwang Sylviane

Abstract excerpt

PURPOSE: Several genes have been recognized, when mutated in the germline, to highly predispose to colorectal cancer, impairing the DNA mismatch repair system in hereditary nonpolyposis colon cancer syndrome, or APC/MYH in adenomatous polyposis. However, 10 percent of microsatellite stable colorectal cancer is reported to develop in an unexplained context of genetic predisposition. This study was designed to...

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Source

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PMID: 17726634
DOI: 10.1007/s10350-007-9040-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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