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Article

Cathepsin B Is Inhibited in Mutant Cells Selected during Persistent Reovirus Infection.

The Journal of biological chemistry - 30 Jan 2004

Ebert Daniel H, Kopecky-Bromberg Sarah A, Dermody Terence S

Abstract excerpt

Persistent reovirus infections of murine L929 (L) fibroblast cells select mutant (LX) cells that do not support proteolytic disassembly of reovirus virions within the endocytic pathway. To better understand the function and regulation of endocytic proteases, we conducted experiments to define the block to reovirus disassembly displayed by LX cells. In contrast to parental L cells, mutant LX cells harbor defects...

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Identifiers

PMID: 14585834
DOI: 10.1074/jbc.M310048200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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