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Article

Dysregulation of autophagy in murine fibroblasts resistant to HSV-1 infection.

PloS one - 1 Jan 2012

Le Sage Valerie, Banfield Bruce W

Abstract excerpt

The mouse L cell mutant, gro29, was selected for its ability to survive infection by herpes simplex virus type 1 (HSV-1). gro29 cells are fully susceptible to HSV-1 infection, however, they produce 2000-fold less infectious virus than parental L cells despite their capacity to synthesize late viral gene products and assemble virions. Because productive HSV-1 infection is presumed to result in the death of the...

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Identifiers

PMID: 22900036
DOI: 10.1371/journal.pone.0042636
PMCID: PMC3416809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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