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Article

Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses.

Journal of virology - 1 Apr 1993

Dermody T S, Nibert M L, Wetzel J D, Tong X, Fields B N

Abstract excerpt

Previous studies demonstrated that both cellular and viral mutants are selected during maintenance of persistent infections established in murine L cells with high-passage stocks of mammalian reoviruses. In particular, when one culture was cured of persistent infection, the resulting cells were found to support the growth of viruses isolated from persistently infected cultures (termed PI viruses here) better than...

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Identifiers

PMID: 8383227
DOI: 10.1128/JVI.67.4.2055-2063.1993
PMCID: PMC240279

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Source receipt: pubmed, retrieved 7 Sept 2026.

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