Article
Neurogenic phenotype of mind bomb mutants leads to severe patterning defects in the zebrafish hindbrain.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2003
Bingham Stephanie, Chaudhari Summer, Vanderlaan Gary, Itoh Motoyuki, Chitnis Ajay, Chandrasekhar Anand
Abstract excerpt
Failure of Notch signaling in zebrafish mind bomb (mib) mutants results in a neurogenic phenotype where an overproduction of early differentiating neurons is accompanied by the loss of later-differentiating cell types. We have characterized in detail the hindbrain phenotype of mib mutants. Hindbrain branchiomotor neurons (BMNs) are reduced in number but not missing in mib mutants. In addition, BMN clusters are...
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