Article
Rhombomere boundaries are Wnt signaling centers that regulate metameric patterning in the zebrafish hindbrain.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2004
Riley Bruce B, Chiang Ming-Yung, Storch Elly M, Heck Rebecca, Buckles Gerri R, Lekven Arne C
Abstract excerpt
The vertebrate hindbrain develops from a series of segments (rhombomeres) distributed along the anteroposterior axis. We are studying the roles of Wnt and Delta-Notch signaling in maintaining rhombomere boundaries as organizing centers in the zebrafish hindbrain. Several wnt genes (wnt1, wnt3a, wnt8b, and wnt10b) show elevated expression at rhombomere boundaries, whereas several delta genes (dlA, dlB, and dlD)...
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