Article
Transcriptome analysis of the zebrafish mind bomb mutant.
Molecular genetics and genomics : MGG - 1 Jan 2009
Hwang Junmo, Kim Hyung-Soo, Seok Ji-Woong, Kim Jun-Dae, Koun Soonil, Park So-Young, Lee Jinseok, Kim Hyang Sook, Kim Hyung-Seok, Kim Kil Soo, Chang Kyu-Tae, Ryoo Zae Young, Wang San Ming, Huh Tae-Lin, Lee Sanggyu
Abstract excerpt
Mind bomb (Mib) facilitates Notch signaling pathway by promoting the endocytosis of Notch ligand. The zebrafish mib ( ta52b ) mutant has a defect in its ubiquitin ligase activity which is necessary to inhibit the neurogenesis, resulting in a neuronal hyperplasia. Several genes regulated in the mi...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
