Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription elongation factor S-II maintains transcriptional fidelity and confers oxidative stress resistance.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Oct 2003

Koyama Hiroshi, Ito Takahiro, Nakanishi Toshiyuki, Kawamura Nobuyuki, Sekimizu Kazuhisa

Abstract excerpt

BACKGROUND: During transcription elongation, RNA polymerase II is arrested on the template when incorrect ribonucleotides are incorporated into the nascent transcripts. Transcription factor S-II enhances the excision of these mis-incorporated nucleotides by RNA polymerase II and stimulates transcription elongation in vitro. This mechanism is considered to be transcriptional proof-reading, but its physiological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcysteine
Share to Antioxidants

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-Galactosidase

Share to Gene Expression Regulation, Fungal

Share to Lac Operon

Share to Operon

Share to Oxidants

Share to RNA Polymerase II

Source

Identifiers

PMID: 14531857
DOI: 10.1046/j.1365-2443.2003.00677.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription elongation factor S-II maintains transcriptional fidelity and confers oxidative stress resistance.PMID 14531857Read ↗

Stimulation of RNA polymerase II transcript cleavage activity contributes to maintain transcriptional fidelity in yeast.Semantic proximity Read ↗

Isolation and characterization of transcription fidelity mutants.Semantic proximity Read ↗

Topoisomerase II is required for the production of long Pol II gene transcripts in yeast.Semantic proximity Read ↗

Defining the divergent enzymatic properties of RNA polymerases I and II.Semantic proximity Read ↗

Nascent RNA folding mitigates transcription-associated mutagenesis.Semantic proximity Read ↗

A third essential DNA polymerase in S. cerevisiae.Semantic proximity Read ↗

Isolation and characterization of RNA polymerase rpoB mutations that alter transcription slippage during elongation in Escherichia coli.Semantic proximity Read ↗

TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress.Semantic proximity Read ↗

Transcription-coupled DNA repair in yeast transcription factor IIE (TFIIE) mutants.Semantic proximity Read ↗

The fidelity of transcription: RPB1 (RPO21) mutations that increase transcriptional slippage in S. cerevisiae.Semantic proximity Read ↗

Genetic interaction between transcription elongation factor TFIIS and RNA polymerase II.Semantic proximity Read ↗

Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.