Article
Transcription-coupled DNA repair in yeast transcription factor IIE (TFIIE) mutants.
Nucleic acids research - 1 Feb 2000
Lommel L, Gregory S M, Becker K I, Sweder K S
Abstract excerpt
We examined the role of yeast transcription initiation factor IIE (TFIIE) in eukaryotic transcription-coupled repair (TCR), the preferential removal of DNA damage from the transcribed strands of genes over non-transcribed sequences. TFIIE can recruit the transcription initiation/repair factor TFIIH to the RNA polymerase II (RNA pol II) initiation complex to facilitate promoter clearance. Following exposure to UV...
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