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Article

A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha.

Pharmacogenetics - 1 Oct 2003

Thompson Miles D, Storm van's Gravesande Karin, Galczenski Helen, Burnham W McIntyre, Siminovitch Kathy A, Zamel Noe, Slutsky Arthur, Drazen Jeffrey M, George Susan R, Evans Jilly F, O'Dowd Brian F

Abstract excerpt

The clinical heterogeneity of asthma suggests that the contribution of genetic variability in candidate gene loci to well-defined phenotypes, such as atopy, may be examined to identify appropriate genetic risk factors for asthma. The gene encoding the cysteinyl leukotriene 2 (CysLT2) receptor has been implicated in atopy since it is localized to a region of chromosome 13q14 that has been linked to atopy in...

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PMID: 14515063
DOI: 10.1097/00008571-200310000-00008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha.PMID 14515063Read ↗

A functional G300S variant of the cysteinyl leukotriene 1 receptor is associated with atopy in a Tristan da Cunha isolate.Semantic proximity Read ↗

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association StudiesSemantic proximity Read ↗

Association of the cysteinyl leukotriene receptor 1 gene with atopy in the British 1958 birth cohort.Semantic proximity Read ↗

A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma.Semantic proximity Read ↗

G-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspective.Semantic proximity Read ↗

The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma.Semantic proximity Read ↗

Association between a polymorphism in cysteinyl leukotriene receptor 2 on chromosome 13q14 and atopic asthma.Semantic proximity Read ↗

927T>C polymorphism of the cysteinyl-leukotriene type-1 receptor (CYSLTR1) gene in children with asthma and atopic dermatitis.Semantic proximity Read ↗

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.Semantic proximity Read ↗

Analysis of 927T> C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma.Semantic proximity Read ↗

Analysis of 927T > C CYSLTR1 and -444A > C LTC4S polymorphisms in children with asthma.Semantic proximity Read ↗

(CCTTT)n repeat polymorphism in the NOS2 gene promoter is associated with atopy.Semantic proximity Read ↗

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