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Article

Analysis of 927T> C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma.

Journal of investigational allergology & clinical immunology - 1 Jan 2006

Sanz C, Isidro-García M, Dávila I, Moreno E, Laffond E, Lorente F

Abstract excerpt

BACKGROUND: The cysteinyl leukotrienes (cys-LTs) are proinflammatory mediators synthesized through the 5-lipoxygenase pathway of arachidonic acid metabolism. Cys-LTs exert their biological action by binding two types of G-protein-coupled seven transmembrane receptors, CYSLTR1 and CYSLTR2. The contribution of the cys-LT receptors to bronchial asthma has been established by the therapeutic efficacy of biosynthetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17153879

Genes

CYSLTR1
CYSLTR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of 927T> C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma.PMID 17153879Read ↗

Analysis of 927T > C CYSLTR1 and -444A > C LTC4S polymorphisms in children with asthma.Semantic proximity Read ↗

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927T>C polymorphism of the cysteinyl-leukotriene type-1 receptor (CYSLTR1) gene in children with asthma and atopic dermatitis.Semantic proximity Read ↗

Cysteinyl‐leukotrienes and their receptors in asthma and other inflammatory diseases: Critical update and emerging trendsSemantic proximity Read ↗

Association of the -1072G/A polymorphism in the LTC4S gene with asthma in an Indian population.Semantic proximity Read ↗

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