Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of 927T > C CYSLTR1 and -444A > C LTC4S polymorphisms in children with asthma.

Allergologia et immunopathologia - 1 Jan 2000

Arriba-Méndez S, Sanz C, Isidoro-García M, Pascual M, Avila C, Dávila I, Lorente F

Abstract excerpt

INTRODUCTION: The cysteinyl leukotrienes (Cys-LTs) are potent inflammatory mediators in asthma. It has been suggested that the different response of patients to Cys-LTs inhibitors could be due to the presence of polymorphisms in the genes implicated in this pathway. METHODS: In this study, polymorphisms 927T > C CYSLTR1 and -444A > C LTC4S were analysed in a Spanish population of 188 individuals (109 asthmatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Asthma
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Glutathione Transferase

Share to Monte Carlo Method

Share to Polymorphism, Genetic

Share to Skin Tests

Source

Identifiers

PMID: 19080797
DOI: 10.1016/s0301-0546(08)75220-0

Genes

CYSLTR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of 927T > C CYSLTR1 and -444A > C LTC4S polymorphisms in children with asthma.PMID 19080797Read ↗

Analysis of 927T> C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma.Semantic proximity Read ↗

927T>C polymorphism of the cysteinyl-leukotriene type-1 receptor (CYSLTR1) gene in children with asthma and atopic dermatitis.Semantic proximity Read ↗

The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma.Semantic proximity Read ↗

Association of the -1072G/A polymorphism in the LTC4S gene with asthma in an Indian population.Semantic proximity Read ↗

The -444A/C polymorphism in the LTC4S gene and the risk of asthma: a meta-analysis.Semantic proximity Read ↗

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association StudiesSemantic proximity Read ↗

A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma.Semantic proximity Read ↗

Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma.Semantic proximity Read ↗

The relevance of CYSLTR1 gene polymorphism to the severity of allergic rhinitis and clinical responsiveness of montelukast in children.Semantic proximity Read ↗

Cysteinyl‐leukotrienes and their receptors in asthma and other inflammatory diseases: Critical update and emerging trendsSemantic proximity Read ↗

Human CYSLTR1 and GSDML gene polymorphisms detection kit provides a new idea for individualized treatment of asthma and improvement of prognosis.Semantic proximity Read ↗

Cysteinyl leukotriene receptor 1 gene variation and risk of asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.